I find the Heart and Brain comic by Nick Seluk both clever and funny. This offshoot of Seluk’s The Awkward Yeti (featuring Lars, the yeti) is described as “the inner dialogue between the cynical, society-influenced Brain and the impulsive, optimistic Heart.” Seluk explains that his “characters were metaphorically inspired by the concept of the Id (Heart), the Ego (Lars) and the Superego (Brain) but have developed their own personalities over time.”
Both the above and below comics feel particularly relevant to me at the moment, but there are so many that I can relate to and that make me laugh. It’s well worth checking out the Heart and the Brain if you haven’t already.
The Question Remains 